We can do genetics. We can do experiments on fruit flies. We can do experiments on yeast. It's not so easy to do experiments on humans. So, in fact, it helps us, to interpret our own genetic code, to have the genetic code of the other species.
Well, we can study aging in people, but of course those studies take decades. So what we try to do is we use simpler organisms to try and understand the basic mechanisms and so in my laboratory, for example, we use things like simple baker's yeast that we use to make bread.
It's been known since 1916 that cutting back calories is beneficial in every organism it's been tested on - from yeast to worms to mice to monkeys. I think it would be a surprise if we are an exception to that rule.
Coproporphyrin in particular is widespread; traces are present in normal urine and also in yeast. In special cultures, yeast can be made to produce considerable quantities of coproporphyrin.
Enthusiasm is the yeast that makes your hopes shine to the stars. Enthusiasm is the sparkle in your eyes, the swing in your gait. The grip of your hand, the irresistible surge of will and energy to execute your ideas.