One cannot plan for the unexpected.
Human curiosity, the urge to know, is a powerful force and is perhaps the best secret weapon of all in the struggle to unravel the workings of the natural world.
My father was trained as a saddler, but in fact as a young man worked in his father's business of rearing and selling cattle, so he grew up in the countryside.
In the course of my stay there, I also showed how one could analyse the experimental kinetic curves for the reaction of haemoglobin with carbon dioxide or oxygen by simulations in the computer, and so fit the rate constants.
Shortly after I was born he emigrated to Durban, where members of my mother's family had settled at the turn of the century, and the rest of the family followed soon thereafter.
Cambridge was the place for someone from the Colonies or the Dominions to go on to, and it was to the Cavendish Laboratory that one went to do physics.
This work made me more and more interested in biological matter, and I decided that I really wanted to work on the X-ray analysis of biological molecules.
However, I should perhaps add that during the 20 years I have been back in Cambridge, I have been actively involved in the teaching of undergraduates, as well as of course supervising research students.
This field is not necessarily glamorous, nor does it often produce immediate results, but it seeks to increase our basic understanding of living processes.
The work requires a moderately large investment in technological and theoretical developments and long periods of time to carry them out, without the pressure to achieve quick or short term results.