The adaptive markets hypothesis says that all economic institutions, like our own species, develop and change over time, depending on the population of investors that are engaged with them.
The greatest problem for mathematicians now is probably the Riemann Hypothesis.
Part of the beauty of Silicon Valley is that people generally encourage you to think crazy. It's the hypothesis that there's nothing sacred that can't be changed.
I think it's outrageous if a historian has a 'leading thought' because it means they will select their material according to their thesis.
My father was among the first of his generation to look into writers who've become part of the American lit. canon. When he wrote his master's thesis on William Faulkner in the Forties, he couldn't find anybody on the faculty at Columbia University to oversee it because they didn't read Faulkner.
Our absolutes should always be hypothesis. They should never be confirmed as fact because everything that we construct through our perceptions, through our memories, is so corruptible. The skills that I have can really display that.
Even if it had not been possible to reproduce the disease in animals and consequently to verify the hypothesis, this simple observation would have been sufficient to demonstrate the way in which the disease was propagated.
I long ago suggested the hypothesis, that in the basin of the Thames there are indications of a meeting in the Pleistocene period of a northern and southern fauna.