I think you can get to a point where nihilism, if that's the right word, is overwhelming, and the basic laws that society has set up - either religious or social laws - become meaningless.
In many ways, anti-anti-Trumpism mirrors Donald Trump himself because, at its core there are no fixed values, no respect for constitutional government or ideas of personal character - only a free-floating nihilism cloaked in insult, mockery, and bombast.
I believe that we are all, openly or secretly, struggling against one or another kind of nihilism.
Horror, almost better than any of the other genres, pits the will to live against the will toward nihilism. I just think that's worth exploring. I don't know what is more important, actually, to explore than that very dynamic.
Scientists are skeptics. It's unfortunate that the word 'skeptic' has taken on other connotations in the culture involving nihilism and cynicism. Really, in its pure and original meaning, it's just thoughtful inquiry.
My grandfather was a practising Quaker. My father was a nihilist. But nihilism, if you like, is the beginning of faith anyway.
The middle way is a view of life that avoids the extreme of misguided grasping born of believing there is something we can find, or buy, or cling to that will not change. And it avoids the despair and nihilism born from the mistaken belief that nothing matters, that all is meaningless.