The Cold War is over but Cold War thinking survives.
All nuclear weapon states should now recognize that this is so, and declare - in Treaty form - that they will never be the first to use nuclear weapons. This would open the way to the gradual, mutual reduction of nuclear arsenals, down to zero.
My third appeal is to my fellow citizens in all countries: Help us to establish lasting peace in the world.
I appeal to my fellow scientists to remember their responsibility to humanity.
If the militarily most powerful - and least threatened - states need nuclear weapons for their security, how can one deny such security to countries that are truly insecure? The present nuclear policy is a recipe for proliferation. It is a policy for disaster.
At a time when science plays such a powerful role in the life of society, when the destiny of the whole of mankind may hinge on the results of scientific research, it is incumbent on all scientists to be fully conscious of that role, and conduct themselves accordingly.
The most terrifying moment in my life was October 1962, during the Cuban Missile Crisis. I did not know all the facts - we have learned only recently how close we were to war - but I knew enough to make me tremble.
The time has come to formulate guidelines for the ethical conduct of scientist, perhaps in the form of a voluntary Hippocratic Oath.
As for the assertion that nuclear weapons prevent wars, how many more wars are needed to refute this arguments? Tens of millions have died in the many wars that have taken place since 1945.
I have to bring to your notice a terrifying reality: with the development of nuclear weapons Man has acquired, for the first time in history, the technical means to destroy the whole of civilization in a single act.
This is the reality of nuclear weapons: they may trigger a world war; a war which, unlike previous ones, destroys all of civilization.
Indeed, the very first resolution of the General Assembly of the United Nations - adopted unanimously - called for the elimination of nuclear weapons.
When the START 2 treaty has been implemented - and remember it has not yet been ratified - we will be left with some 15,000 nuclear warheads, active and in reserve. Fifteen thousand weapons with an average yield of 20 Hiroshima bombs.
But scientists on both sides of the iron curtain played a very significant role in maintaining the momentum of the nuclear arms race throughout the four decades of the Cold War.
Several studies, and a number of public statements by senior military and political personalities, testify that - except for disputes between the present nuclear states - all military conflicts, as well as threats to peace, can be dealt with using conventional weapons.
To sum up, there is no evidence that a world without nuclear weapons would be a dangerous world. On the contrary, it would be a safer world, as I will show later.
Indeed, the whole human species is endangered, by nuclear weapons or by other means of wholesale destruction which further advances in science are likely to produce.