The evolvement of proteolysis as a centrally important regulatory mechanism is a remarkable example for the development of a novel biological concept and the accompanying battles to change paradigms.
Given the rapid rate of change, the old paradigm of one-off education followed by a career will no longer work: life-long learning is a must, and it is up to governments and employers to invest in training and for employees to commit to constantly update their skill set.
I am a little suspicious of industry paradigms. I feel like so many movies and TV shows feel so familiar because of over-reliance on these paradigms.
People don't use Evite or Facebook events for their weddings. But they do use Paperless Post. It's the sign of a paradigm because it is the most momentous occasion in most people's lives. It represents the most formal type of offline communication.
The progressive integration of new technologies in our economy amounts to a paradigm shift with a profound impact on the context and content of work.
Almost all the knowledge required to produce more food than eroding soil is available today - we just need to use that knowledge within a holistic paradigm - managing agriculture holistically, forming the policies that undergird it holistically.
When I speak of diversity, I don't mean replacement of white comics. I don't mean acceptance by white comics. We comics who weren't born into the white guy paradigm of 'funny' don't need a handout. We don't need a PC push. We don't need 'a look.'
Every time you see a new paradigm emerge, it's always new vendors that lead it. I can't think of one case where an incumbent led a paradigm shift.
My typical paradigm is that I do believe in public service. My father's a military man. He really does always speak about the fact that there is actually nothing more valuable that you can do than actually to serve your country. And I buy that.
I love how New York as an idea is less a paradigm of manifest destiny and more a romance for the social orphans of the world. We live here to be among the towers and the crowds.
