Grey's Anatomy
Grey's Anatomy

Dr. Meredith Grey: Sometimes reality has a way of sneaking up and biting us in the ass. And when the dam bursts, all you can do is swim. The world of pretend is a cage, not a cocoon. We can only lie to ourselves for so long. We are tired, we are scared, denying it doesn't change the truth. Sooner or later we have to put aside our denial and face the world. Head on, guns blazing.

De Nile. It's not just a river in Egypt, it's a freakin' ocean. So how do you keep from drowning in it?

Grey's Anatomy
Grey's Anatomy

Dr. Meredith Grey: Did you let me scrub in for this operation because I slept with you?
Dr. Derek Shepherd: Yes.
[pause]
Dr. Derek Shepherd: Just kidding.

Grey's Anatomy
Grey's Anatomy

Dr. Derek Shepherd: It's not the chase.
Dr. Meredith Grey: What?
Dr. Derek Shepherd: You and me. It is not the thrill of the chase. It's not a game. It's... it's your tiny ineffectual fists. And your hair.
Dr. Meredith Grey: My hair?
Dr. Derek Shepherd: It smells good. And you're very,

very ballsy. It keeps me in line.
Dr. Meredith Grey: I'm still not going out with you.
Dr. Derek Shepherd: You say that now...

Grey's Anatomy
Grey's Anatomy

Dr. Preston Burke: So, I have a question to ask. I checked the schedule and I noticed that both you and I are off tonight. I made reservations. I have a favorite restaurant.
Dr. Cristina Yang: None of those were questions.

Grey's Anatomy
Grey's Anatomy

[to Meredith]
Dr. Cristina Yang: Burke wants to have a relationship... Boys are stupid.

Grey's Anatomy
Grey's Anatomy

Dr. Derek Shepherd: So we're kissing but we're not dating?
Dr. Meredith Grey: I knew that was going to come up.
Dr. Derek Shepherd: Don't get me wrong: I like the kissing. I'm all for the kissing. More kissing, I say.
Dr. Meredith Grey: I have no idea what that was about.
Dr. Derek

Shepherd: Is it going to happen again? 'Cause if it is, I need to bring breath mints.
[whispers]
Dr. Derek Shepherd: Put a condom in my wallet.
Dr. Meredith Grey: Shut up, now!

Grey's Anatomy
Grey's Anatomy

Dr. Cristina Yang: You are eight feet tall. Your boobs are perfect. Your hair is down to there. If I was you I would just walk around naked all the time. I wouldn't have a job, I wouldn't have any skills, I wouldn't even know how to read. I would just be... naked.
Dr. Isobel "Izzie" Stevens: It's makeup. It's retouching.
Dr. Cristina

Yang: You get that we hate you, right?

Grey's Anatomy
Grey's Anatomy

Dr. Isobel "Izzie" Stevens: [to Alex] You wanna see it? You really wanna see it? Fine! Let's look at that tattoo up close and personal, shall we?
[she rips off her shirt]
Dr. Isobel "Izzie" Stevens: What are these? Oh, my God! Breasts! How does anybody practice medicine hauling these things around? And what have we got back here? Lets see if I

remember my anatomy.
[takes off her pants]
Dr. Isobel "Izzie" Stevens: Gluts, right? Lets study them, shall we? Gather around and check out the booty that put Izzie Stevens through Med. school! You wanna call me Dr. Model? That's fine. But just remember that while you're all still sitting on 200 grand of student loans, I'm out of debt.

Grey's Anatomy
Grey's Anatomy

Dr. Meredith Grey: My mommy's a filthy whore.

Grey's Anatomy
Grey's Anatomy

Dr. Derek Shepherd: [to Addison] Christmas makes you want to be with people you love. I'm not saying this to hurt you, or because I want to leave you, because I don't. Meredith wasn't a fling. She wasn't revenge. I fell in love with her. That doesn't go away because I decided to stay with you.

Grey's Anatomy
Grey's Anatomy

Dr. Meredith Grey: At the end of the day, when it comes down to it, all we really want is to be close to somebody. So this thing, where we all keep our distance and pretend not to care about each other, is usually a load of bull. So we pick and choose who we want to remain close to, and once we've chosen those people, we tend to stick close by. No matter how much we hurt them, the

people that are still with you at the end of the day - those are the ones worth keeping. And sure, sometimes close can be too close. But sometimes, that invasion of personal space, it can be exactly what you need.

Grey's Anatomy
Grey's Anatomy

Dr. Meredith Grey: You know how when you were a little kid and you believed in fairy tales, that fantasy of what your life would be, white dress, prince charming who would carry you away to a castle on a hill. You would lie in bed at night and close your eyes and you had complete and utter faith. Santa Claus, the Tooth Fairy, Prince Charming, they were so close you could taste

them, but eventually you grow up, one day you open your eyes and the fairy tale disappears. Most people turn to the things and people they can trust. But the thing is its hard to let go of that fairy tale entirely cause almost everyone has that smallest bit of hope, of faith, that one day they will open their eyes and it will come true.

Grey's Anatomy
Grey's Anatomy

Dr. Meredith Grey: [about her new roommates] They're everywhere. All the time. Izzie's all perky and George does this where he's helpful and considerate. They share food, and they say things, and they move things, and they breathe. Ugh, they're, like, happy
Dr. Cristina Yang: Kick them out.
Dr. Meredith Grey: I can't kick them out,

they just moved in. I asked them to move in.
Dr. Cristina Yang: So what, you're just going to repress everything in some deep, dark, twisted place until one day you snap and you kill them?

Grey's Anatomy
Grey's Anatomy

Dr. Meredith Grey: I've heard that it's possible to grow up - I've just never met anyone who's actually done it. Without parents to defy, we break the rules we make for ourselves. We throw tantrums when things don't go our way, we whisper secrets with our best friends in the dark, we look for comfort where we can find it, and we hope - against all logic, against all experience.

Like children, we never give up hope...

Grey's Anatomy
Grey's Anatomy

Dr. Isobel "Izzie" Stevens: [standing in the bathroom, outside the shower, where George is] I reminded you before you went.
Dr. George O'Malley: I forgot when I got there.
Dr. Isobel "Izzie" Stevens: No.
[she opens the shower door]
Dr. Isobel "Izzie" Stevens: No, you were so passive aggressive!

Dr. George O'Malley: Naked! I am naked in the shower!
Dr. Isobel "Izzie" Stevens: [closes the shower door] Just tampons, George! I really needed tampons. God!
[Meredith enters the bathroom]
Dr. Isobel "Izzie" Stevens: I'm not riding in the same car as him.
Dr. Meredith Grey: [looks at Izzie, who is

standing in her "Hello Kitty" underwear] Unless you're going like that, you're not riding with me either. Where are the tampons?
Dr. Isobel "Izzie" Stevens: He didn't buy them.
Dr. Meredith Grey: [to George] You didn't buy them?
Dr. George O'Malley: Men don't buy tampons!
Dr. Isobel "Izzie" Stevens:

[opens the shower door again, and George falls over] You know what? You're gonna have to get over the whole man thing, George! We're women! We have vaginas! Get used to it!
[she walks out of the bathroom, leaving George lying on the floor of the shower]
Dr. George O'Malley: I am not your sister!
[he slams the shower door]

Grey's Anatomy
Grey's Anatomy

Dr. Alex Karev: When your life is sucky you get drunk and sleep with inappropriate men. It's your thing.

Grey's Anatomy
Grey's Anatomy

Dr. George O'Malley: You know Joe?
Dr. Miranda Bailey: Oh, yeah. I was the only female intern my year. I didn't know anybody and nobody knew me except Joe. He knew me.
Dr. George O'Malley: Oh. So you and Joe...?
Dr. Miranda Bailey: All you people ever think about is how to get into somebody's pants. You're

nasty.
[slaps George]
Dr. Miranda Bailey: That's why you got syphilis.

Grey's Anatomy
Grey's Anatomy

Dr. Meredith Grey: Maybe we're not supposed to be happy. Maybe gratitude has nothing to do with joy. Maybe being grateful means recognizing what you have for what it is. Appreciating small victories. Admiring the struggle it takes to simply be human. Maybe, we're thankful for the familiar things we know. And maybe we're thankful for the things we'll never know. At the end of the

day, the fact that we have the courage to still be standing is reason enough to celebrate.

Grey's Anatomy
Grey's Anatomy

Dr. Cristina Yang: I get angry when I go without sleep.

Grey's Anatomy
Grey's Anatomy

Dr. Meredith Grey: At the end of the day faith is a funny thing. It turns up when you don't really expect it. It's like one day you realize that the fairy tale may be slightly different than you dreamed. The castle, well, it may not be a castle. And it's not so important happy ever after, just that its happy right now. See once in a while, once in a blue moon, people will surprise

you , and once in a while people may even take your breath away.