I run a modest-sized laboratory that's looking specifically at what we call 'the pathogenic mechanisms of HIV disease, or AIDS.'
Pneumococcal disease is a real threat. Pneumococcal disease is a bacterial infection that causes anything from middle ear infection to pneumonia to meningitis. Children are particularly vulnerable to it, but adults can get pneumococcal disease themselves.
When a company is fairly certain of a profit margin that is substantial, it can assume responsibility for the clinical trials to develop a blockbuster drug.
There are so many different varieties of HIV out there.
When you think in terms of public service, I heard so much about what Mother Theresa had done in her life. And I was fortunate enough to get a chance to meet her and talk to her a lot about what motivates her and what drives her. And that, to me, is a person that really is an extraordinary role model.
The immune system's goal is to protect the body against invaders either from without, such as microbes, or from within, such as cancers and different types of neoplastic transformation.
There are a number of candidate vaccines that are in development for HIV/AIDS.
Some of the most vulnerable people to getting the SARS virus are health care providers. The general public, walking in the street, there is really not that much risk at all. It's a very, very low risk - a very, very low risk.
You might be asking too much if you're looking for one vaccine for every conceivable influenza. If you have one or two that cover the vast majority of isolates, I wouldn't be ashamed to call that a 'universal vaccine.'
For the first time, we have the genetic sequences of all three of the players in the global malaria debacle: the parasite, the anopheles mosquito and the human. It's a very important milestone.
There has been treatment for hepatitis C, but the treatment has not been overwhelmingly effective, number 1. And number 2, it has had considerable toxicity.
I'm generally considered a conservative in my predictions for disease.
The launch of phase 1 Ebola vaccine studies is a first step in developing a vaccine that could be licensed and used in the field to protect not only the front line health care workers but also those living in areas where Ebola virus exists.
There's always the danger when you have influenzas that infect chickens, that when you have the close quarters of chickens spreading from one to another and occasionally a human coming into close contact, that there will be the jumping of species from a chicken to a human. This is not something new.