I think you can have a ridiculously enormous and complex data set, but if you have the right tools and methodology then it's not a problem.
We didn't set out to be educators or even scientists, and we don't purport that what we do is real science but we're demonstrating a methodology by which one can engage and satisfy your curiosity.
The palladium-catalyzed cross-coupling reaction between different types of organoboron compounds and various organic electrophiles including halides or triflates in the presence of a base provides a powerful and general methodology for the formation of carbon-carbon bonds.
I feel now, as we did then, that for an effective approach to the problem of nucleic acid biosynthesis, it was essential to understand the biosynthesis of the simple nucleotides and the coenzymes and to have these concepts and methodology well in hand.
Now along comes the potential creative destruction brought by a different distribution methodology, the Internet.
Any Wall Street advertising that does not go into the boring details of methodology is most likely to be pushing past performance.
Some of the most significant advances in molecular biology have relied upon the methodology of genetics. The same statement may be made concerning our understanding of immunological phenomena.
I don't really consider myself to be an actor of any particular style. My aim with every role I undertake is to be truthful and honest in that particular portrayal. I don't have a particular methodology from any one school of thought or training.
I think polling methodology is broken.