The detection of gravitational waves is truly a triumph of modern large-scale experimental physics.
I never understood how one could write a whole book: It is so technically challenging, and it's incredible the way writers put entire worlds inside of them on such a large scale. I tend to have that same feeling when I listen to music - it daunts me and makes me feel quite unsettled listening to so much talent and ambition.
With every inch of land on Earth now catalogued by our satellites, the stars are the next place we as a species must travel. And with a booming world population that will hit 9.1 billion in 2050, large-scale space travel may become a necessity.
Whenever Congress undertakes large-scale reform, there are times when disaster appears certain - only to be averted at the last minute by the good sense of its sometimes unfairly maligned members.
'Too big to fail' is fine for restaurant chains. If Denny's fails, it's fine for this economy. You can always go down to the TGIFs. But that's not the same for large-scale investment companies.
Smart and savvy, the fearless female member of George Washington's Secret Six is a testament to the strong women who have helped to alter the course of history in this great nation, both in terms of large-scale battles and in the new opportunities they have helped create for future generations through their own fearless examples.
Criminal and terrorist threats are morphing beyond traditional actors and tactics. We still have to worry about things like an al-Qaida cell plotting a large-scale attack, but we also now have to worry increasingly about homegrown violent extremists radicalizing in the shadows.
'Clothespin' was the first city monument on a large scale that could compete with the architecture around it.
I am not that concerned that innovation in some large scale sense will suddenly and abruptly shift from one part of the world to another.
'Dead Aid' is about the inefficacy and the limitations of large-scale aid programs in creating economic growth and reducing poverty in Africa.
