I think it is important for readers to know that it is possible to bring intellectualism and idealism to the White House and still be political enough to advance an agenda.
Both for my wife and myself, the personal friendships that have grown out of scientific contacts with colleagues from many different countries have been an important part of our lives, and the travels we have made together in connection with the world-wide scientific co-operation have given us rich treasures of experiences.
There must be a story within him/her that wants to come out. That's the reason why 'Dil Chahta Hai,' 'Lagaan,' and 'Rang De Basanti' worked so well: Ashutosh, Farhan, and Rakesh had a story inside them. It's very important that the director should have the fire in the belly to tell the story.
When material comes to me, I don't care where it's coming from. Japan, Singapore, China, Africa... it could be from everywhere. The material should excite me. It's not important where it's coming from.
The evolvement of proteolysis as a centrally important regulatory mechanism is a remarkable example for the development of a novel biological concept and the accompanying battles to change paradigms.
Towards the end of the military service, I had to make what I assume has been the most important decision in my career: to start a residency in clinical medicine, in surgery, which was my favorite choice, or to enroll into graduate school and start a career in scientific research. It was clear to me that I was heading for graduate school.
The problem of different sensitivities of distinct protein groups to lysosomal inhibitors has remained unsolved and may have served as an important trigger in the future quest for a non-lysosomal proteolytic system that may be involved in at least certain aspects of intracellular protein degradation.
The important thing is to do what you most love in the best way. If you love literature, you could be a great writer and perhaps one day become a Nobel Prize Laureate for Literature.
I think they are very important because westerns have a code and a symbolism.