The problem of different sensitivities of distinct protein groups to lysosomal inhibitors has remained unsolved and may have served as an important trigger in the future quest for a non-lysosomal proteolytic system that may be involved in at least certain aspects of intracellular protein degradation.
Reticulocytes are terminally differentiating red blood cells that do not contain lysosome. Therefore, it was postulated that the degradation of hemoglobin in these cells is mediated by a non-lysosomal machinery.
I suppose one has a greater sense of intellectual degradation after an interview with a doctor than from any human experience.
One has a greater sense of degradation after an interview with a doctor than from any human experience.
It was a feeling of loyalty to our own sex and an enthusiasm to have every degradation that was put upon our sex removed.
I believe we need to attract a new generation of the best and brightest to public service and I believe that government can be a source of inspiration, not degradation.
War is a blessing compared with national degradation.
Judging by my degradation in the last 24 hours, I'll be surprised if I make it to Tuesday.